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Horseradish (Armoracia rusticana, Cochlearia armoracia)
Also listed as: Armoracia rusticana, Cochlearia armoracia
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Related Terms
- Allyl isothiocyanate, allylisothiocyanate, Armoracia lapathifolia Gilib., Armoracia rusticana, Armoracia rusticana Gaertner, Armoracia sativa Heller, Amoraciae Rusticanae Radix, Bohemian horseradish, Brassicaceae (family), Cochlearia armoracia, Cochlearia rusticana Lamarck, common horseradish, glucobrassicin, gluconasturtiin, glucosinolates, great raifort, horseradish peroxidase, horseradish peroxidase/indole-3-acetic acid, isoenzymes, isothiocyanates, Meerrettich (German), mountain radish, myrosinase, neoglucobrassicin, pepperrot, phosphatidylcholines, red cole, seiyowasabi (Japanese), sinigrin, thioglucoside conjugates, Western wasabi.
- Note: This monograph does not include wasabi (Wasabia japonica), for which horseradish is a common substitute.
- Note: The U.S. Food and Drug Administration (FDA) defines horseradish as the root of Armoracia lapathifolia Gilib. This monograph uses the more common scientific name Armoracia rusticana, which is used by the U.S. Department of Agriculture (USDA).
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Background
- Horseradish (Armoracia rusticana) is a hardy perennial plant of the Brassicaceae family, which includes mustard and cabbage. Large doses by mouth can cause gastrointestinal upset, bloody vomiting, diarrhea, and irritation of mucous membranes and the urinary tract. Horseradish may also provoke allergic reactions.
- Although horseradish may be irritating, it is frequently used as a condiment or spice, especially for beef, sausages, and fish. The U.S. Food and Drug Administration (FDA) has approved horseradish (Armoracia lapathifolia Gilib.) as Generally Recognized as Safe (GRAS) as a seasoning, spice, and flavoring (the FDA currently accepts Armoracia lapathifolia as the binomial name for horseradish, although Armoracia rusticana is more commonly used and is the preferred name by the U.S. Department of Agriculture).
- Traditionally, horseradish has been used for pain, rheumatism, and cancer. It has also been studied for bronchitis, sinusitis, and urinary tract infections, but additional study is needed before making firm recommendations.
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Evidence Table
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These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. |
GRADE * |
Horseradish may have antibiotic activity, and has been used in combination with other herbs to treat bronchitis. However, additional studies are needed that use horseradish as a single therapy before a strong recommendation can be made.
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C |
Horseradish may have antibiotic activity, and has been used in combination with other herbs to treat sinusitis. However, additional studies are needed that use horseradish as a single therapy before a strong recommendation can be made.
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C |
Horseradish may have antibiotic activity, and has been used in combination with other herbs to treat urinary tract infections. However, additional studies are needed that use horseradish as a single therapy before a strong recommendation can be made.
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C |
* Key to grades
A: Strong scientific evidence for this use B: Good scientific evidence for this use C: Unclear scientific evidence for this use D: Fair scientific evidence for this use (it may not work) F: Strong scientific evidence against this use (it likley does not work)
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Tradition / Theory
The below uses are based on tradition, scientific theories, or limited research. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider. There may be other proposed uses that are not listed below.
- Abortion, allergies, anodyne (pain-reliever), antibiotic, anticoagulant (blood thinner), antihypertensive (blood pressure-lowering), anti-inflammatory, antimutagenic, arthritis, blood cleanser, bruises, cancer, carminative (relieves gas), childbirth (expelling afterbirth), colic, cough, diaphoretic (promotes sweating), digestive, diuretic (increases urine flow), dropsy (swelling), edema (swelling), emetic (induces vomiting), expectorant (encourages coughing up of mucous), fever, food uses, gallbladder disorders, gout (foot inflammation), headaches, hoarseness, infections, inflammation, intestinal worms (in children), lower back pain, muscle aches, neuralgia (facial nerve pain), paralysis, pleurisy (lung inflammation), respiratory disorders, rheumatism (painful disorder of the joints, muscle, or connective tissue), saliva stimulant, sciatica (irritation of the sciatic nerve resulting in pain or tingling running down the inside of the leg), scurvy, skin conditions (rubefacient), skin fairness, stimulant, tuberculosis, urinary stones, wounds.
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DosingAdults (over 18 years old)
- There is no proven safe or effective medicinal dose of horseradish in adults.
Children (under 18 years old)
- There is no proven safe or effective medicinal dose of horseradish in children.
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Attribution
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This information is based on a systematic review of scientific literature edited and peer-reviewed by contributors to the Natural Standard Research Collaboration (www.naturalstandard.com).
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Bibliography
- Agabeili RA, Kasimova TE, Alekperov UK. [Antimutagenic activity of plant extracts from Armoracia rusticana, Ficus carica and Zea mays and peroxidase in eukaryotic cells]. Tsitol.Genet. 2004;38(2):40-45.
- Agabeili RA, Kasimova TE. [Antimutagenic activity of Armoracia rusticana, Zea mays and Ficus carica plant extracts and their mixture]. Tsitol.Genet. 2005;39(3):75-79.
- Conaway CC, Yang YM, Chung FL. Isothiocyanates as cancer chemopreventive agents: their biological activities and metabolism in rodents and humans. Curr Drug Metab 2002;3(3):233-255.
- Goos KH, Albrecht U, Schneider B. [Efficacy and safety profile of a herbal drug containing nasturtium herb and horseradish root in acute sinusitis, acute bronchitis and acute urinary tract infection in comparison with other treatments in the daily practice/results of a prospective cohort study]. Arzneimittelforschung 2006;56(3):249-257.
- Govere EM, Tonegawa M, Bruns MA, et al. Using minced horseradish roots and peroxides for the deodorization of swine manure: a pilot scale study. Bioresour.Technol 2007;98(6):1191-1198.
- Kawaoka A, Matsunaga E, Endo S, et al. Ectopic expression of a horseradish peroxidase enhances growth rate and increases oxidative stress resistance in hybrid aspen. Plant Physiol 2003;132(3):1177-1185.
- Li X, Kushad MM. Purification and characterization of myrosinase from horseradish (Armoracia rusticana) roots. Plant Physiol Biochem 2005;43(6):503-511.
- Luczaj L, Szymanski WM. Wild vascular plants gathered for consumption in the Polish countryside: a review. J Ethnobiol.Ethnomedicine. 2007;3:17.
- Park IK, Choi KS, Kim DH, et al. Fumigant activity of plant essential oils and components from horseradish (Armoracia rusticana), anise (Pimpinella anisum) and garlic (Allium sativum) oils against Lycoriella ingenua (Diptera: Sciaridae). Pest.Manag.Sci 2006;62(8):723-728.
- Patterson AV, Saunders MP, Greco O. Prodrugs in genetic chemoradiotherapy. Curr Pharm Des 2003;9(26):2131-2154.
- Sakuyama H, Endo Y, Fujimoto K, et al. Oxidative degradation of alkylphenols by horseradish peroxidase. J Biosci.Bioeng. 2003;96(3):227-231.
- Tonegawa M, Dec J, Bollag JM. Use of additives to enhance the removal of phenols from water treated with horseradish and hydrogen peroxide. J Environ.Qual. 2003;32(4):1222-1227.
- Veitch NC. Horseradish peroxidase: a modern view of a classic enzyme. Phytochemistry 2004;65(3):249-259.
- Weil MJ, Zhang Y, Nair MG. Colon cancer proliferating desulfosinigrin in wasabi (Wasabia japonica). Nutr Cancer 2004;48(2):207-213.
- Weil MJ, Zhang Y, Nair MG. Tumor cell proliferation and cyclooxygenase inhibitory constituents in horseradish (Armoracia rusticana) and Wasabi (Wasabia japonica). J Agric Food Chem 3-9-2005;53(5):1440-1444.
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Copyright © 2011 Natural Standard (www.naturalstandard.com)
| The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.
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